US-MA-Cambridge: Senior Scientist I Medicinal Chemistry
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mistry.html
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Date: 02-Sep-2008
Scientist II/III or Senior Scientist I Medicinal Chemistry
Job Description:
Job Description: The in***bent will propose targets, design early
stage synthetic routes, oversee outsourced production of milligram to
gram quantities of compounds, contribute to the development of
structure-activity relation****ps (SAR) of synthesized compounds and
manage CRO synthesis activities leading to process scale-up. A strong
background in synthetic organic chemistry, chemical development, and
analytical chemistry combined with excellent leader****p and
communications skills will be essential in this dynamic role.
Minimum Education & Experience Requirements: Ph.D. or PharmD with
emphasis in organic and/or medicinal chemistry or related discipline.
1-2+ years of experience preferred. Masters degree in synthetic
organic and/or medicinal chemistry or related discipline with 5+ years
of immediately relevant experience may be considered
Knowledge/Skills Needed: Background in synthetic organic or medicinal
chemistry required, with experience in biochemistry, pharmacology or
enzymology and analytical chemistry preferred. Experience in
preparation of manuscripts, CRO management, technical re****ts and
sections of regulatory submission do***ents (eg: INDs, CTDs) a plus.
=95 Demonstrated experience with design and execution of multi-step
synthesis of small molecules or natural products =95 Ability to manage
and provide guidance to CRO chemists conducting syntheses =95 Ability to
convey organic chemistry ideas and subjects to non-chemists =95 A
background in understanding the biology and treatment of addiction. =95
Interest in the design of drugs to target reward disorders with an
initial focus on molecules targeting the opioid receptors =95 Strong
understanding of current analytical chemistry methodology and assay
development; hands-on experience a plus =95 Scientific writing and
presentation skills are essential; peer reviewed publications in a
relevant field required =95 Familiarity with chemistry drawing software
Thank you,
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